中文名 | 盐酸依伐布雷定 |
英文名 | Ivabradine hydrochloride |
别名 | 盐酸伊伐布雷 盐酸伊伐布雷定 盐酸依伐布雷定 盐酸伊伐布雷啶 盐酸依法布雷定 依伐布雷定盐酸盐 盐酸伊伐布雷定及中间体 盐酸伊伐布雷定(依法布雷定) 盐酸伊伐布雷定IVABRADINE(研发中) 3-[3-[[(8S)-3,4-二甲氧基-8-双环[4.2.0]辛-1,3,5-三烯]甲基-甲氨基]丙基]-7,8-二甲氧基-2,5-二氢-1H-3-苯并氮杂卓-4-酮盐酸盐 |
英文别名 | Corlentor Ivabradine HCl Ivabradine hydrochloride IVABRADINE HYDROCHLORIDE-OTHER COMPOUNDSConTAINING AN UNFUSED PYRAZOLE RING(WHETHER OR NOT HYDROGENATED)IN THE STRUCTUR 3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride |
CAS | |
EINECS | |
化学式 | C27H36N2O5.HCl |
分子量 | 505.05 |
InChI | InChI=1/C27H36N2O5.ClH/c1-28(-25(33-4)26(34-5)16-22(20)21)8-6-9-29-(31-2)24(32-3)13-19(18)15-27(29)30;/hH,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1 |
InChIKey | HLUKNZUABFFN |
熔点 | 193-196?C |
沸点 | 626.9°C at 760 mmHg |
比旋光度 | 58921 +7.8°; 36521 +27.8° (c = 1% in DMSO) |
闪点 | 332.9°C |
蒸汽压 | 1.24E-15mmHg at 25°C |
溶解度 | H2O: ≥5mg/mL (warmed) |
存储条件 | 2-8°C |
外观 | powder |
颜色 | white to beige |
Merck | 14,5247 |
MDL号 | MFCD00929899 |
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